Calcium, cancer and killing: The role of calcium in killing cancer cells by cytotoxic T lymphocytes and natural killer cells☆

Eva C. Schwarz, Bin Qu, Markus Hoth ⁎ Department of Biophysics, Saarland University, Homburg, Germany Abstract Killing cancer cells by cytotoxic T lymphocytes (CTL) and by natural killer (NK) cells is of vital importance. Cancer cell proliferation and apoptosis depend on the intracellular Ca2+ concentration, and the expression of numerous ion channels with the ability […]