Eun-Hee Cho, Keun-Hyok Cho, Hyang Ah Lee, and Sang-Wook Kim Abstract Osteopontin (OPN) is an acidic, noncollagenous matrix protein produced by the bone and kidneys. It is reportedly involved in bone resorption and formation. We examined the association between serum OPN levels and bone mineral density in postmenopausal women. Premenopausal women (n = 32) and […]
Nutrients 2013, 5, 3964-3974; doi:10.3390 / nu5103964 / ISSN 2072-6643 Abstract: Concern has recently arisen about the potential adverse effects of excessive calcium intakes, i.e., calcium loading from supplements, on arterial calcification and risks of cardiovascular diseases (CVD) in older adults. Published reports that high calcium intakes in free-living adults have relatively little or […]
Prevalance of Osteoporosis: 28 million Americans (10 million with osteoporosis; 18 million with low bone mass); eight million American women and 2 million men (NWHIC) Read Full Article
– The new England journal of medicine METHODS In a phase 2, multicenter, international, randomized, placebo-controlled, parallel group, eight-group study, we evaluated the efficacy and safety of romosozumab over a 12-month period in 419 postmenopausal women, 55 to 85 years of age, who had low bone mineral density (a T score of −2.0 or less at […]