Cancer stem cell Why does cancer recur? Already in 1877, Virchow’s student Cohnheim noticed this cell population and pointed out that it possesses an embryonic character*. Today, those cells are called cancer stem cells (CSCs) or tumor-initiating cells (TICs) and are seen as drivers of tumor establishment and growth, often correlated to aggressive, heterogeneous and […]
SAC(Sigma Anti-bonding Calcium Carbonate) Study with GCaMP on Zebra Fish By Prof. Sandra Rieger, Sylvester Comprehensive Cancer Center, University of Miami, Jan. 2021 As shown in the following figure, D depicts the fluorescent cells which were analyzed. Zebrafish transient microinjections result was in a mosaic expression; therefore, only some cells expressed the GCaMP. A red […]
Wei Qiao, Hui En Lau, Huizhi Xie, Vincent Kwok-Man Poon, Chris Chung-Sing Chan,Hin Chu, Shuofeng Yuan, Terrence Tsz-Tai Yuen, Kenn Ka-Heng Chik, Jessica Oi-Ling Tsang, Chris Chun-Yiu Chan, Jian-Piao Cai, Cuiting Luo, Kwok-Yong Yuen, Kenneth Man-Chee Cheung, Jasper Fuk-Woo Chan & Kelvin Wai-Kwok Yeung Abstract Extrapulmonary complications of different organ systems have been increasingly recognized […]
JIHWAN SONG , Syed Hassan Mehdi, Sae Woong Oh, Jongsung Lee, Paul K Lee, Alex Lee, Yong Gu Lee, and Donghoon Yoon Abstract Sigma Anti-Bonding Molecule Calcium Carbonate (SAC) is a chemically modified calcium carbonate with a unique weak bonding structure that significantly increases the calcium absorbing rate in our body. It can influence environmental […]
Bo Abrahamsen, Clive Osmond and Cyrus Cooper Abstract Osteoporosis is a chronic disease, carrying an elevated risk of fractures, morbidity, and death. Long-term treatment may be required, but the long-term risks with osteoporosis drugs remain incompletely understood. The competing risk of death may be a barrier to treating the oldest, yet this may not be […]
Amanda Devine, R Arthur Criddle, Ian M Dick, Deborah A Kerr, and Richard L Prince Abstract The influence of urinary sodium excretion and dietary calcium intake was examined in a 2-y longitudinal study of bone density in 124 women postmenopausal for > 10 y. Analysis of bone density changes showed that urinary sodium excretion was […]
So-Yeon Lee, Eun Lee, Yoon Mee Park, Soo-Jong Hong Abstract The microbiome is vital for immune system development and homeostasis. Changes in microbial composition and function, termed dysbiosis, in the skin and the gut have recently been linked to alterations in immune responses and to the development of skin diseases, such as atopic dermatitis (AD). […]
Mi Nam Lee, Hee-Su Hwang, Sin-Hye Oh, Amir Roshanzadeh, Jung-Woo Kim, Ju Han Song, Eung-Sam Kim and Jeong-Tae Koh Abstract Supplementation of mesenchymal stem cells (MSCs) at sites of bone resorption is required for bone homeostasis because of the non-proliferation and short lifespan properties of the osteoblasts. Calcium ions (Ca 2+ ) are released from […]
Eun-Hee Cho, Keun-Hyok Cho, Hyang Ah Lee, and Sang-Wook Kim Abstract Osteopontin (OPN) is an acidic, noncollagenous matrix protein produced by the bone and kidneys. It is reportedly involved in bone resorption and formation. We examined the association between serum OPN levels and bone mineral density in postmenopausal women. Premenopausal women (n = 32) and […]
Andrew P. Landstrom, Dobromir Dobrev and Xander H.T. Wehrens Abstract There has been a significant progress in our understanding of the molecular mechanisms by which calcium (Ca 2+ ) ions mediate various types of cardiac arrhythmias. A growing list of inherited gene defects can cause potentially lethal cardiac arrhythmia syndromes, including catecholaminergic polymorphic ventricular tachycardia, […]